While Oklahoma State and TCU advanced through the winners' bracket to set up a possible all–Big 12 championship, Arizona and Coastal Carolina won both elimination games to advance to the best-of-three final series. Tech eventually became the fourth team to be eliminated. In the CWS after Texas Tech lost to Big 12 rival TCU, none of the three national seeds who had reached Omaha had won their opening game. For the first time since the tournament expanded from 48 teams in 1999, the NCAA did not select any Pac-12 schools to host a regional, and Lubbock, Texas ( Texas Tech) was the westernmost regional host city picked by the selection committee. A tournament-high seven regional hosts came from the Southeastern Conference (SEC), followed by six of the ten ACC schools however, only Miami (ACC) and Florida (SEC) advanced to Omaha, and they were the first and second teams eliminated, respectively. The Atlantic Coast Conference (ACC) set a conference record and tied the all-time mark of having ten teams in the championship field.

Regional champions faced each other in Super Regionals, a best-of-three-game series to determine the eight participants of the College World Series. Teams were divided into sixteen regionals of four teams, which conducted a double-elimination tournament. Thirty-one teams were awarded an automatic bid, as champions of their conferences the remaining 33 teams were selected at-large by the NCAA Division I Baseball Committee. The 64 participating NCAA Division I college baseball teams were selected out of 298 eligible teams. The 64-team, double-elimination tournament concluded with the 2016 College World Series (CWS) in Omaha, Nebraska, starting on June 18, 2016, and ending on June 30, 2016. The 2016 NCAA Division I Baseball Tournament began on Friday, June 3, 2016, as part of the 2016 NCAA Division I baseball season.

2016 world series baseball